Due to a grim prognosis, there is an urgent need to detect pancreatic ductal adenocarcinoma (PDAC) prior to metastasis.However, reliable diagnostic imaging methods or biomarkers for PDAC or its precursor lesions are still scarce.ADAM8, a metalloprotease-disintegrin, is highly expressed in PDAC tissue and negatively correlates with patient survival.
Obstructive sleep apnea (OSA) patients are at risk for increased blood pressure and carotid intima-media thickness (IMT), with pulmonary hypertension and right-sided heart failure potentially developing as well.Chronic intermittent hypoxia (IH) has been used as an OSA model in animals, but its effects on vascular beds have not been evaluated using
Introduction: Abortion was legalized in Nepal in September 2002.Only a trained and listed provider can provide abortion services at a health.For many Printers women, especially in developing countries like Nepal, safe abortion may not be available, affordable or accessible despite the liberalization of abortion law.The aim of this study was to dete
Regina Fölster-Holst,1 Jagoda Galecka,1 Sigo Weißmantel,1 Ute Dickschat,2 Frank Rippke,3 Kerstin Bohnsack,3 Thomas Werfel,4 Katja Wichmann,4 Matthias Buchner,1 Thomas Schwarz,1 Annika Vogt,5 Jürgen Lademann,5 Martina C Meinke5 1Department of Dermatology, Venerology and Allergy, University of Kiel, 2Wörth, 3Beiersdorf AG, Hambur
Histone acetylation is an important posttranslational modification correlated with gene activation.In Arabidopsis thaliana the histone acetyltransferase (HAC) proteins of the CBP family are homologous to animal p300/CREB (cAMP-responsive element-binding proteins, which are Goalie - Chest Protectors - Senior important histone acetyltransferases part